News Feature Channel: Liver Disease

Roswell Park-Led Research Reveals a Hidden Vulnerability of Lung Cancer

Roswell Park Comprehensive Cancer Center — Thu, 10 Apr 2025 17:55:38 EST

Treatment resistance and relapse in the most common type of lung cancer can be traced to a protein called agrin, according to a preclinical study led by Roswell Park. Results of the study, led by Sayan Chakraborty, PhD, Assistant Professor of Oncology at Roswell Park, appear in Advanced Science.

Two Angels, a Robot and 23: A Johns Hopkins Medicine Organ Transplant Story

Johns Hopkins Medicine — Tue, 08 Apr 2025 10:45:17 EST

A Johns Hopkins Medicine Organ Transplant Story

Gluten-Free Diet and Arsenic Exposure, Virtual CBT for IBS, and More in the April Issue of AJG

American College of Gastroenterology (ACG) — Tue, 08 Apr 2025 09:00:08 EST

he April issue of The American Journal of Gastroenterology highlights new clinical science and reviews, including the gluten-free diet and exposure to arsenic, internet-delivered cognitive behavior therapy for irritable bowel syndrome, a new guideline on gastric premalignant conditions, and multi-society consensus recommendations on bowel preparation.

Endocrine Society Disappointed in Failure to Extend Medicare and Medicaid Coverage to Anti-Obesity Medications

Endocrine Society — Mon, 07 Apr 2025 23:05:13 EST

The Endocrine Society is extremely disappointed the administration has chosen not to finalize a rule that would have made anti-obesity medications more accessible to millions of Americans with obesity.

Gastrointestinal Disease Costs U.S. More Than $100 Billion, UNC Researchers Estimate

University of North Carolina Health Care System — Mon, 07 Apr 2025 22:15:47 EST

A new study, led by researchers at the UNC School of Medicine, highlights the latest statistics on gastrointestinal cancers, hospital admissions, liver transplants, and research funding.

Trasplantes de higado ofrecen una nueva esperanza a los pacientes con cancer colorrectal con metastasis hepatica

Mayo Clinic — Mon, 07 Apr 2025 08:00:51 EST

Los trasplantes de higado se estan convirtiendo en una nueva opcion de tratamiento para algunos pacientes con cancer colorrectal cuyos canceres se han diseminado al higado y no son elegibles para otros tipos de cirugia. Este enfoque innovador ha traido esperanza a los pacientes con cancer colorrectal que, de otro modo, a menudo enfrentan un pronostico sombrio.

Transplantes de figado oferecem uma nova esperanca aos pacientes com cancer colorretal com metastase hepatica

Mayo Clinic — Mon, 07 Apr 2025 08:00:18 EST

Os transplantes de figado estao se tornando uma nova opcao de tratamento para alguns pacientes com cancer colorretal cujos canceres se espalharam para o figado e nao sao elegiveis para outros tipos de cirurgia. Essa abordagem inovadora tem trazido esperanca para pacientes com cancer colorretal que, de outra forma, costumam enfrentar um prognostico sombrio.

زراعة الكبد تحمل أملًا جديدًا لمرضى سرطان القولون والمستقيم المصابين بنقائل الكبد

Mayo Clinic — Mon, 07 Apr 2025 08:00:09 EST

أصبحت عمليات زراعة الكبد خيارًا علاجيًا جديدًا متاحًا لبعض مرضى سرطان القولون والمستقيم الذين انتقل السرطان لديهم للكبد مما جعلهم غير مؤهلين لخيارات جراحية أخرى. يمنح هذا النهج المبتكر الأمل لمرضى سرطان القولون والمستقيم والذين بخلاف ذلك غالبًا ما يتلقون تنبؤات قاتمة بخصوص مآل المرض.

Stiffness Measurement Without Organoid Damage Aids Drug Development for Fatty Liver Disease

National Research Council of Science and Technology — Wed, 02 Apr 2025 00:00:53 EST

The research team led by Dr. Hyunwoo Kim and Dr. Myungae Bae at the Korea Research Institute of Chemical Technology (KRICT) has developed the nano-probe-based quantitative stiffness measurement technique for a non-alcoholic fatty liver disease (NAFLD) simulate artificial organoid model while minimizing tissue damage.

Liver Transplants Offer New Hope for Colorectal Cancer Patients with Liver Metastasis

Mayo Clinic — Tue, 01 Apr 2025 10:15:04 EST

Liver transplants are becoming a new treatment option for certain colorectal cancer patients whose cancer has spread to their liver and are ineligible for other surgical options. This innovative approach is providing hope to colorectal cancer patients who otherwise are often faced with a grim prognosis.

Jacob Bilhartz, M.D., Available to Discuss Vitamin A Supplements and Potential Liver Injury in Children

Michigan Medicine - University of Michigan — Fri, 28 Mar 2025 18:30:34 EST

Yale Surgeons to Present at International Surgical Oncology Conference

Yale Cancer Center/Smilow Cancer Hospital — Mon, 24 Mar 2025 10:55:32 EST

Yale Department of Surgery oncologists and trainees at Yale Cancer Center will present new findings at the Society of Surgical Oncology (SSO) Annual Meeting in Tampa, Fla., from March 27-29. The conference focuses on improving surgical cancer care for patients through educational sessions as well as oral and poster presentations for surgical oncologists, researchers, and patient advocates.

Cedars-Sinai Appoints New Chair of Department of Medicine

Cedars-Sinai — Thu, 20 Mar 2025 23:35:42 EST

Following a comprehensive national search, Cedars-Sinai has appointed David E. Cohen, MD, PhD, as the new chair of the Department of Medicine, effective July 1.

Liver Supplements - Hype or Harm?

Hackensack Meridian Health — Tue, 18 Mar 2025 09:10:53 EST

Unlocking the Secrets of HBV: New Hope for Chronic Hepatitis B Cure

Chinese Academy of Sciences — Mon, 17 Mar 2025 11:00:02 EST

Chronic hepatitis B virus (HBV) infection continues to pose a major global health threat. The virus evades immune responses and antiviral therapies due to the persistence of covalently closed circular DNA (cccDNA), which serves as a viral reservoir.

GLP-1 Use Before Endoscopy, Resuming Blood Thinners after ESD, and More in the March Issue of AJG

American College of Gastroenterology (ACG) — Mon, 10 Mar 2025 19:35:02 EST

In the March issue of The American Journal of Gastroenterology: The effect of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) on gastric retention before endoscopy, resumption of blood thinners after colorectal submucosal dissection, and the utility of inpatient GI consults to clear patients for transesophageal echocardiogram.

Diesel Exhaust Exposure Led to Disarray in Liver Function in Mice

University of California, Los Angeles (UCLA), Health Sciences — Tue, 04 Mar 2025 11:00:04 EST

STIM1: The Cancer Shield Against Sorafenib Unmasked

Chinese Academy of Sciences — Tue, 04 Mar 2025 08:20:58 EST

A recent study unveils how stromal interaction molecule 1 (STIM1), a protein involved in calcium signaling, plays a pivotal role in the resistance of liver cancer to sorafenib, a key treatment for advanced hepatocellular carcinoma (HCC).

Metabolic Shift in Liver Cancer: How PDHX Acetylation Drives Tumor Growth

Chinese Academy of Sciences — Mon, 03 Mar 2025 05:50:37 EST

A recent study has unveiled a new mechanism driving hepatocellular carcinoma (HCC) progression through the acetylation of pyruvate dehydrogenase complex (PDC) component X (PDHX), a critical component of the PDC. This modification disrupts PDC assembly, inhibits its function, and shifts metabolism towards aerobic glycolysis, promoting tumor growth. The findings highlight PDHX acetylation as both a potential biomarker and therapeutic target, offering new possibilities for liver cancer treatment and advancing our understanding of cancer cell metabolism.

Cedars-Sinai Sets New Record in Organ Transplantation

Cedars-Sinai — Fri, 28 Feb 2025 18:45:11 EST

The Cedars-Sinai Comprehensive Transplant Center and the Smidt Heart Institute set a new record in 2024 by completing 682 solid organ transplants--the most the medical center has performed in a year--as patient survival outcomes continued to meet or exceed the national average.