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Ҵý: AACR: New CAR T Cell Therapy Benefits Patients with Advanced Thyroid Cancers
Released: 29-Apr-2025 11:15 AM EDT
AACR: New CAR T Cell Therapy Benefits Patients with Advanced Thyroid Cancers
University of Texas MD Anderson Cancer Center

• Phase I trial demonstrates lasting responses and encouraging safety profile in two aggressive thyroid cancer subtypes, suggesting further progress for CAR T cell therapy in solid tumors • One patient experienced a complete response, and one patient had a partial response • This type of cancer has limited treatment options, and most patients have a poor prognosis of six months or less • AIC100 is a CAR T cell therapy that targets the ICAM-1 protein on tumor cells

Ҵý: AACR: HER2 targeted therapy shows promise in previously treated lung cancers
Released: 28-Apr-2025 9:00 AM EDT
AACR: HER2 targeted therapy shows promise in previously treated lung cancers
University of Texas MD Anderson Cancer Center

• Zongertinib, a HER2-targeted therapy made by Boehringer Ingelheim, demonstrated promising results in HER2-mutant lung cancer

Ҵý: AACR: First-in-Class Covalent Werner Helicase Inhibitor Shows Clinical Proof-of-Concept in Phase I Trial
Released: 27-Apr-2025 4:30 PM EDT
AACR: First-in-Class Covalent Werner Helicase Inhibitor Shows Clinical Proof-of-Concept in Phase I Trial
University of Texas MD Anderson Cancer Center

• RO7589831, a new drug from Roche, is first in a new class of drugs called Werner helicase inhibitors • Drug works similarly to other DNA damage repair inhibitors, such as PARP inhibitors • This class of drugs is important because many solid tumor patients with microsatellite instability (MSI) do not benefit from currently approved immunotherapies • Encouraging early results in this first-in-human trial prompted additional trial cohorts to optimize recommended dose for future clinical development

Ҵý: AACR: Topical gel relieves painful skin rash side effect caused by targeted therapy for colorectal cancer
Released: 27-Apr-2025 4:30 PM EDT
AACR: Topical gel relieves painful skin rash side effect caused by targeted therapy for colorectal cancer
University of Texas MD Anderson Cancer Center

· LUT014, a topical BRAF inhibitor made by Lutris Pharma, is the first agent to treat the cause of the rash without interfering with the treatment itself · Over two-thirds of patients had successful treatment with the higher dose of LUT014 compared to one-third with placebo

Ҵý: AACR: Olaparib and Pembrolizumab Combination Shows Early Promise in Molecularly Selected, Tumor-Agnostic Trial
Released: 27-Apr-2025 2:00 PM EDT
AACR: Olaparib and Pembrolizumab Combination Shows Early Promise in Molecularly Selected, Tumor-Agnostic Trial
University of Texas MD Anderson Cancer Center

• Combining Lynparza (olaparib) and Keytruda (pembrolizumab) showed antitumor activity in multiple cancer types, particularly those with BRCA1/2 mutations • Combination demonstrated complete responses and partial responses in different cancer types, including those beyond the currently approved indications for these therapies

Released: 25-Apr-2025 1:00 PM EDT
AACR: Researchers share promising results from MD Anderson clinical trials
University of Texas MD Anderson Cancer Center

Researchers from The University of Texas MD Anderson Cancer Center will present promising results from clinical trials in three minisymposia abstracts at the American Association for Cancer Research (AACR) Annual Meeting 2025. Findings include a personalized vaccine combination therapy for colorectal cancer, the use of radiotherapy to avoid the toxicities of systemic treatments for kidney cancer, and engineered exosomes to silence mutant KRAS in pancreatic cancer.

   
Released: 21-Apr-2025 7:25 PM EDT
AACR: Five MD Anderson researchers honored with 2025 Scientific Achievement Awards
University of Texas MD Anderson Cancer Center

Five scientists from The University of Texas MD Anderson Cancer Center will be recognized with Scientific Achievement Awards and honors at the American Association for Cancer Research (AACR) Annual Meeting 2025.

Ҵý: AACR: MD Anderson’s John Weinstein elected Fellow of the AACR Academy
Released: 18-Apr-2025 10:00 AM EDT
AACR: MD Anderson’s John Weinstein elected Fellow of the AACR Academy
University of Texas MD Anderson Cancer Center

John N. Weinstein, M.D., Ph.D., chair of Bioinformatics and Computational Biology and professor of Systems Biology at The University of Texas MD Anderson Cancer Center, has been elected to the 2025 class of Fellows of the American Association for Cancer Research (AACR) Academy in recognition of decades of combined laboratory and computational work pioneering multi-omic molecular profiling, including the introduction of new laboratory techniques, clustered heat maps, and early innovations in artificial intelligence for cancer drug discovery.

   
Released: 17-Apr-2025 12:00 PM EDT
MD Anderson Research Highlights for April 17, 2025
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

   
Released: 4-Apr-2025 5:00 AM EDT
NK Cells Complexed with Bispecific Antibody Yield High Response Rates in Patients with Lymphoma
University of Texas MD Anderson Cancer Center

A novel cell therapy approach using cord blood-derived natural killer (NK) cells pre-complexed with AFM13, or acimtamig, a CD30/CD16A bispecific antibody, was safe and generated strong response rates for patients with refractory CD30-positive lymphomas, according to a new study from The University of Texas MD Anderson Cancer Center.

Ҵý: MD Anderson Breaks Ground on New Sugar Land Location
Released: 31-Mar-2025 7:10 PM EDT
MD Anderson Breaks Ground on New Sugar Land Location
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center today broke ground on a new 470,000-square-foot facility in Sugar Land, bringing a range of cancer services and MD Anderson’s unparalleled patient experience closer to those living in Southwest Houston and the surrounding areas.

Ҵý: Surgery May Not Be Necessary to Treat Invasive Breast Cancer
Released: 28-Mar-2025 8:00 AM EDT
Surgery May Not Be Necessary to Treat Invasive Breast Cancer
University of Texas MD Anderson Cancer Center

Surgery may not be the best next course of treatment for patients with early-stage breast cancer who had a complete response to neoadjuvant (pre-surgical) chemotherapy and standard radiation treatment, according to new data from researchers at The University of Texas MD Anderson Cancer Center.

Released: 27-Mar-2025 6:10 PM EDT
MD Anderson Research Highlights for March 27, 2025
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

   
Ҵý: Two MD Anderson Researchers Elected AAAS Fellows
Released: 27-Mar-2025 5:20 AM EDT
Two MD Anderson Researchers Elected AAAS Fellows
University of Texas MD Anderson Cancer Center

In recognition of their significant achievements to advance cancer care and research, Lauren Byers, M.D., and Paul Scheet, Ph.D., from The University of Texas MD Anderson Cancer Center have been elected fellows of the American Association for the Advancement of Science (AAAS).

Ҵý: MD Anderson names Jeffrey E. Lee, M.D., Chief Medical Executive
Released: 26-Mar-2025 9:05 PM EDT
MD Anderson names Jeffrey E. Lee, M.D., Chief Medical Executive
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center today announced that Jeffrey E. Lee, M.D., an internationally regarded leader in the field of oncology, has been appointed chief medical executive (CME) effective April 1.

Released: 12-Mar-2025 12:00 PM EDT
MD Anderson Research Highlights for March 12, 2025
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

   
Released: 5-Mar-2025 8:25 AM EST
F. W. Bert and Mae Dean Wheeler Foundation Establishes Nurse Leadership Academy at MD Anderson with $9 Million Gift
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center today announced a $9 million gift from the F. W. Bert and Mae Dean Wheeler Foundation to establish the F. W. Bert and Mae Dean Wheeler Nurse Leadership Academy.

Released: 26-Feb-2025 4:45 PM EST
MD Anderson Research Highlights for February 26, 2025
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

   
Ҵý: MD Anderson Researchers Develop Novel Antibody-Toxin Conjugate
Released: 25-Feb-2025 5:00 AM EST
MD Anderson Researchers Develop Novel Antibody-Toxin Conjugate
University of Texas MD Anderson Cancer Center

Researchers at The University of Texas MD Anderson Cancer Center have developed a novel antibody-toxin conjugate (ATC) designed to stimulate immune-mediated eradication of tumors. According to preclinical results published today in Nature Cancer, the new approach combined the benefits of more well-known antibody-drug conjugates (ADCs) with those of immunotherapies.

Released: 19-Feb-2025 9:10 PM EST
UT MD Anderson and Texas Children’s Hospital Announce Joint Venture to End Childhood Cancer
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center and Texas Children’s Hospital have announced a transformational collaboration dedicated solely to pediatric cancer care. The collaboration has a single mission: to end childhood cancer.



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