Assessing Systemic Sclerosis With AI Deep Neural Networks
Yale School of MedicineArtificial intelligence (AI) is shaping the future of health care, offering new tools for earlier diagnosis of disease and more precise tracking of treatment outcomes.
Artificial intelligence (AI) is shaping the future of health care, offering new tools for earlier diagnosis of disease and more precise tracking of treatment outcomes.
Systemic sclerosis, or scleroderma, causes the hardening of skin and connective tissues. Often, the disease harms other organs, such as the heart, kidneys, lungs, and gastrointestinal tract, and it can lead to death.
After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown in a new study how activity of “good” microbes in the gut is linked to rheumatoid arthritis and, potentially, other autoimmune diseases.
Investigators at the UNC School of Medicine have gained a clearer understanding of what causes the rare autoimmune condition that inflames blood vessels.
Mountainside Medical Group is excited to welcome Nitya Ramreddy, M.D., to its growing team of expert providers. Dr. Ramreddy is a board-certified rheumatologist dedicated to delivering compassionate, patient-centered care with a focus on collaboration and long-term wellness.
Although rheumatoid arthritis is an autoimmune disease with no cure, a tailored, multidisciplinary treatment approach at Cedars-Sinai’s Inflammatory Arthritis Clinical Center helps patients get back to the activities they enjoy.
Indiana University School of Medicine scientists have developed a new imaging technique to study bone marrow in mouse models. This advancement could support future drug development and therapies for conditions involving bone marrow, including cancers, autoimmune diseases and musculoskeletal disorders.
Wistar and collaborators have discovered a type of “molecular glue” that can be used to inhibit certain pathological protein interactions.
Those who suffer myasthenia gravis experience muscle weakness that can affect the muscles we use to blink, smile and move our bodies. Researchers at UC San Diego’s School of Biological Sciences used a cutting-edge imaging technique to uncover new details about the mechanisms underlying the disease.
In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, QRICH1, which could become a target for drugs to dial up or down the activation of T cells to fight cancers and autoimmune diseases.
Research in mice shows that inflammatory molecules influence mood and behavior by acting on specific brain regions. The findings help explain why some people experience lasting mood changes after infections or autoimmune disease flare-ups. The research could lead to new therapies for anxiety disorders and autism spectrum disorders
A significant discovery has identified a missing "gatekeeper" protein as the root cause of dry mouth in Sjögren's syndrome — a finding that could change the way the disease is treated. Researchers pinpointed tricellulin, a protein that helps seal the junctions between saliva gland cells, as the key factor. When inflammation damages tricellulin, saliva production stops and harmful substances leak through.
Parents of children who have been diagnosed with multiple sclerosis likely have many questions about their child’s condition. Receiving a diagnosis can be overwhelming and searching for information online can turn up complicated explanations.Laura Saucier, MD, MSc, a neuroimmunologist in the Neurological Institute at Children’s Hospital Los Angeles, breaks down the key information that parents should know about multiple sclerosis (MS).
For years, an unnamed disease slowly stole one man's sight—until his son’s diagnosis finally provided the answer. Their journey highlights how rare disease research can unravel medicine's most elusive mysteries and, in doing so, can help reshape the future of medicine.
Researchers are studying messenger RNA’s potential to treat and prevent an array of serious conditions—including cancer.
COVID infection has been linked to higher risk of autoimmune disorders, including rheumatoid arthritis and type 1 diabetes. Scientists used advanced data analysis and machine learning to identify viral proteins that are more likely to trigger autoimmunity.
Nebraska undergrads uncover ancient secrets of human immunity
New research from the University of Chicago shows how a specially trained population of immune cells keeps the peace by preventing other immune cells from attacking their own.
Scientists at Washington University School of Medicine in St. Louis and the Perelman School of Medicine at the University of Pennsylvania have identified a key component to launching immune activity – and overactivity. The researchers identified a protein in cells that spurs the release of infection-fighting molecules. The protein, whose role in the immune system had not previously been suspected, provides a potential target for therapies that could prevent overreactive immune responses that are at the root of several debilitating illnesses.
Protein kinase research presents an opportunity to explore molecular targets in the body to treat diseases like cancer and autoimmune disorders. These enzymes have the potential to bind to cellular sites and inhibit dysfunctional behavior, such as the overproduction of cancerous cells and tumor formation.